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Friday, 12 November 2010

Get Rhythm When You Get The Blues

Genes that regulate circadian rhythm were examined in people with and without a history of depression and found that those with a history of depression had a higher level of activity in this gene.

Higher expression levels of this gene could affect sleep patterns and other physiological functions governed by circadian rhythm - this is highly interesting as Sleep disturbance is a common symptom of depression.

This is only a link, it cannot be inferred either way whether the gene difference is the cause or the effect of depression but it does advance what we know about depression and brain structures that seem to indicate it.

In terms of advances in treatment, those with depressions and this genetic profile may benefit most from sleep-related treatments: Light therapy or a antidepressants that act on melatonin (a sleep regulatory hormone.)

Link to Article

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